CAS Number: 863288-34-0
Molecular Formula: C₁₆H₂₇N₅O₄
Molecular Weight: 353.42 g/mol
Form: Lyophilized powder
Purity: ≥ 98% (HPLC)
Storage Conditions: –20 °C, protected from light and moisture
Intended Use: For laboratory research use only. Not for human or veterinary applications.
KPV is a synthetic tripeptide fragment (Lys-Pro-Val) derived from the alpha-melanocyte–stimulating hormone (α-MSH) sequence.
It has been widely studied for its anti-inflammatory, antimicrobial, and tissue-protective properties, particularly in research exploring immune regulation and barrier-function restoration.
In preclinical research, KPV has demonstrated the ability to modulate NF-κB activity, reduce pro-inflammatory cytokine release, and enhance epithelial repair responses.
These characteristics make it a valuable tool for immunology, dermatology, and gastrointestinal-barrier research models.
Studies on inflammatory cytokine modulation and immune response regulation.
Research involving epithelial healing, barrier integrity, and wound repair mechanisms.
Antimicrobial and antioxidant pathway investigations.
Use as a reference compound in peptide signaling and inflammation-control studies.
Form: Lyophilized powder (white to off-white)
Purity: ≥ 98% (HPLC verified)
Reconstitution: Reconstitute with sterile water or buffer prior to use.
Storage: Store at –20 °C in a sealed vial; avoid repeated freeze–thaw cycles.
Shelf Life: 24 months under recommended storage conditions.
Safety: For research use only. Handle using appropriate laboratory safety procedures.